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Giuseppe Paradies Selected Research

Cardiolipins (Cardiolipin)

11/2018Mitochondrial bioenergetics and cardiolipin alterations in myocardial ischemia-reperfusion injury: implications for pharmacological cardioprotection.
6/2015Protective role of melatonin in mitochondrial dysfunction and related disorders.
10/2014Oxidative stress, cardiolipin and mitochondrial dysfunction in nonalcoholic fatty liver disease.
10/2013Decline in cytochrome c oxidase activity in rat-brain mitochondria with aging. Role of peroxidized cardiolipin and beneficial effect of melatonin.
3/2011Mitochondrial dysfunction in brain aging: role of oxidative stress and cardiolipin.
5/2010Oxidative stress, mitochondrial bioenergetics, and cardiolipin in aging.
5/2010Melatonin, cardiolipin and mitochondrial bioenergetics in health and disease.
10/2009Melatonin protects against heart ischemia-reperfusion injury by inhibiting mitochondrial permeability transition pore opening.
10/2009Melatonin inhibits cardiolipin peroxidation in mitochondria and prevents the mitochondrial permeability transition and cytochrome c release.
6/2009Role of cardiolipin peroxidation and Ca2+ in mitochondrial dysfunction and disease.
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Giuseppe Paradies Research Topics

Disease

12Mitochondrial Diseases (Mitochondrial Disease)
11/2018 - 10/2007
6Ischemia
10/2009 - 03/2002
4Reperfusion Injury
11/2018 - 04/2003
2Non-alcoholic Fatty Liver Disease
10/2014 - 10/2007
1Myocardial Ischemia (Ischemic Heart Diseases)
11/2018
1Infarction (Infarctions)
10/2009
1Heart Failure
06/2009
1Mitochondrial complex I deficiency
01/2009
1Fatty Liver
10/2007

Drug/Important Bio-Agent (IBA)

16Cardiolipins (Cardiolipin)IBA
11/2018 - 04/2003
6Reactive Oxygen Species (Oxygen Radicals)IBA
11/2018 - 03/2002
5MelatoninIBA
11/2017 - 10/2008
2Mitochondrial Permeability Transition PoreIBA
11/2018 - 10/2009
2Cytochromes c (Cytochrome c)IBA
10/2009 - 11/2006
2AntioxidantsIBA
10/2009 - 10/2008
1Electron Transport Complex IV (Cytochrome c Oxidase)IBA
10/2013
1L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA
10/2009
1NAD (NADH)IBA
10/2009
11- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)IBA
10/2009
1Choline (Choline Chloride)IBA
10/2007
1Electron Transport Complex III (Coenzyme Q-Cytochrome-c Reductase)IBA
04/2003